Macromolecular assemblies at the crossroads of cell stress and function
EMBO | Workshop: Macromolecular assemblies at the crossroads of cell stress and function. 31 May – 4 June 2015, Jerusalem (Israel).
Workshop Web Site: Follow this Link
Recent work has highlighted the sub-organellar meso-scale of protein organization has gained increasing attention as an essential mediator of protein folding, function, proteostasis, transcription, translation, and RNA metobolism. In particular, stress-induced RNP granules and protein inclusions are emerging as essential elements of the quality control architecture on one hand, and causal agents of several age-associated diseases on the other hand. These nano-scale macromolecular assemblies (or Dynamic Droplets) provide a platform for rapid protein and nucleic acid transport, and for rapid response to changing conditions, but can also serve as targets for pertrubation by dysfunctional proteins…
- RNP granules in RNA quality control and dynamics
- Meso-scale organization of protein mixtures and phase transitions in the cytoplasm
- Aggregation, stress, and brain diseases
- RNA and Neurodegeneration
- Cellular architecture of protein quality control and aggregation
- Aging, replicative rejuvenation, and asymmetric inheritance
- Inclusions in cellular regulation and disease
- Protein degratation in proteostasis and quality control
- 15 February 2015, Early registration
- 1 April 2015, Late registration and Abstract submision
- Find more information in the Workshop Web Site.
- See here a complete list of 2015 EMBO Events.