Category: Jul. 2019

“Papers of the Month” by SBE members (July 2019)

DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region. Nucleic Acids Res. 2019 Jul 9;47(12):6519-6537. doi: 10.1093/nar/gkz406.

Highlights2019 / Jul. 2019

13/09/2019

DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region

Cuppari A, Fernandez-Millan P, Battistini F, Tarres-Sole A, Lyonnais S, Iruela G, Ruiz-Lopez E, Enciso Y, Rubio-Cosials A, Prohens R, Pons M, Alfonso C, Toth...

Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13680-13689. doi: 10.1073/pnas.1900430116.

Highlights2019 / Jul. 2019

10/09/2019

Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology

Pittolo S, Lee H, Llado A, Tosi S, Bosch M, Bardia L, Gomez-Santacana X, Llebaria A, Soriano E, Colombelli J, Poskanzer KE, Perea G, Gorostiza...

Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility. Nucleic Acids Res. 2019 Jul 2;47(W1):W300-W307. doi: 10.1093/nar/gkz321.

Highlights2019 / Jul. 2019

06/09/2019

Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility

Kuriata A, Iglesias V, Pujols J, Kurcinski M, Kmiecik S, Ventura S. Nucleic Acids Res 2019 Jul; 47: W300. Protein aggregation is a hallmark...

Why are some Enzymes Dimers? Flexibility and Catalysis in Thermotoga Maritima Dihydrofolate Reductase. ACS Catal. 2019 Jul 5;9(7):5902-5911. doi: 10.1021/acscatal.9b01250.

Highlights2019 / Jul. 2019

06/09/2019

Why are some Enzymes Dimers? Flexibility and Catalysis in Thermotoga Maritima Dihydrofolate Reductase

Ruiz-Pernia JJ, Tuñón I, Moliner V, Allemann RK. ACS Catal 2019 Jul; 9: 5902. Dihydrofolate Reductase from Thermotoga maritima (TmDFHFR) is a dimeric thermophilic...