Category: Apr. 2019

“Papers of the Month” by SBE members (April 2019)

Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α.Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8000-8009. doi: 10.1073/pnas.1817183116.

Apr. 2019 / Highlights2019

20/05/2019

Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-alpha

Nieto-Gonzalez JL, Gomez-Sanchez L, Mavillard F, Linares-Clemente P, Rivero MC, Valenzuela-Villatoro M, Munoz-Bravo JL, Pardal R, Fernandez-Chacon R. Proc Natl Acad Sci U S...

Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8. Science. 2019 Apr 26;364(6438). pii: eaav9011. doi: 10.1126/science.aav9011.

Apr. 2019 / Highlights2019

20/05/2019

Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma8

Herguedas B, Watson JF, Ho H, Cais O, Garcia-Nafria J, Greger IH. Science 2019 Apr; 364: eaav9011. AMPA-type glutamate receptors (AMPARs) mediate excitatory neurotransmission...

L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction. Nat Commun. 2019 Apr 18;10(1):1807. doi: 10.1038/s41467-019-09837-z.

Apr. 2019 / Highlights2019

20/05/2019

L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction

Errasti-Murugarren E, Fort J, Bartoccioni P, Diaz L, Pardon E, Carpena X, Espino-Guarch M, Zorzano A, Ziegler C, Steyaert J, Fernandez-Recio J, Fita I, Palacin...

Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8699-8708. doi: 10.1073/pnas.1813194116.

Apr. 2019 / Highlights2019

15/05/2019

Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion

Lakomek NA, Yavuz H, Jahn R, Perez-Lara A. Proc Natl Acad Sci USA 2019 Apr; 116: 8699. Intrinsically disordered proteins (IDPs) and their conformational...