Protein aggregation: Toxicity and function, two sides of the same coin
Protein aggregation: Toxicity and function, two sides of the same coin Salvador Ventura, IBB-UAB, Barcelona (Spain) download Protein misfolding and aggregation are linked to...
Tagged: Amyloid
Mompeán…Laurents {Front Mol Neurosci 9: 125}
An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds Mompeán M, Baralle M, Buratti E, Laurents DV. Front Mol Neurosci 2016 Nov.;...
Predoctoral Position in Protein Biophysics
The group of Biophysics and Molecular Biotechnology of the University of Granada is offering a predoctoral position to a highly qualified and motivated graduate student...
Molina-García…Giraldo {Sci Rep 6: 25425}
Functional amyloids as inhibitors of plasmid DNA replication Molina-García L, Gasset-Rosa F, Moreno-Del Álamo M, Fernández-Tresguerres ME, Moreno-Díaz de la Espina S, Lurz R, Giraldo...
Mompeán…Laurents {PLoS Biol 14: e1002447}
Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation Mompeán M, Chakrabartty A, Buratti E, Laurents DV. PLoS Biol 2016 Apr.; 14: e1002447. TDP-43 is a protein...
Fernández…Giraldo {Sci Rep 6: 23144}
RepA-WH1, the agent of an amyloid proteinopathy in bacteria, builds oligomeric pores through lipid vesicles Fernández C, Núñez-Ramírez R, Jiménez M, Rivas G, Giraldo R....
Sant’Anna…Ventura {Nat Commun 7: 10787}
Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity Sant’Anna R, Gallego P, Robinson LZ, Pereira-Henriques A, Ferreira N, Pinheiro F,...
Martínez…Gasset {Sci Rep 5:13623}
PrP charge structure encodes interdomain interactions Martínez J, Sánchez R, Castellanos M, Makarava N, Aguzzi A, Baskakov IV, Gasset M. Sci Rep. 2015 Sep; 5:13623....
Chen…Cremades {PNAS 112: E1994}
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation Chen SW, Drakulic S, Deas E, Ouberai M, Aprile FA, Arranz R,...
Torreira…Llorca {Structure 23: 183}
Amyloidogenesis of Bacterial Prionoid RepA-WH1 Recapitulates Dimer to Monomer Transitions of RepA in DNA Replication Initiation. Torreira E, Moreno-Del Álamo M, Fuentes-Perez ME, Fernández C,...