Fernández…Giraldo {Sci Rep 6: 23144}

RepA-WH1, the agent of an amyloid proteinopathy in bacteria, builds oligomeric pores through lipid vesicles. Sci Rep. 2016 Mar 17;6:23144. doi: 10.1038/srep23144.
The bacterial prionoid RepA-WH1 builds pores at model lipidic membranes. Left: mCherry-tagged RepA-WH1 (red) binds to and leaks the contents (calcein, green) of liposomes. Right: Average EM 2D-projection of a ring oligomer with its constituent RepA-WH1 monomers fitted.