Rujas…Nieva {Sci Rep 6: 38177}

Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface. Sci Rep. 2016 Dec 1;6:38177.
Structural model for 10E8 epitope binding. Formation of a complex at the viral membrane interface, stabilized by phospholipids and aromatic residues from both, the antibody CDR-H3 and the MPER-TMD helix, (inset) interrupts progression of the fusion process and, therefore, viral infection