López-Perrote…Llorca {Nucleic Acids Res 44: 1909}

3D model of the complex between nonsense-mediated mRNA decay factor UPF2 and eukaryotic release factor eRF3. The model was obtained using electron microscopy (EM) of purified eRF3-UPF2 complexes, and atomic structures of some domains were fitted into the EM model. One of the major findings in Lopez-Perrote et al. is the discovery that UPF2 interacts with eRF3 and the biochemical and structural characterisation of this complex.