Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go
Garcia-Nafria J, Nehme R, Edwards PC, Tate CG. Nature 2018 Jun; 558: 620. G-protein-coupled receptors (GPCRs) form the largest family of receptors encoded by...
Tagged: Molecular Interactions
Anomalously low dielectric constant of confined water
Fumagalli L, Esfandiar A, Fabregas R, Hu S, Ares P, Janardanan A, Yang Q, Radha B, Taniguchi T, Watanabe K, Gomila G, Novoselov KS, Geim...
Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa
Lee M, Batuecas MT, Tomoshige S, Dominguez-Gil T, Mahasenan KV, Dik DA, Hesek D, Millan C, Uson I, Lastochkin E, Hermoso JA, Mobashery S. ...
Force determination in lateral magnetic tweezers combined with TIRF microscopy
Madariaga-Marcos J, Hormeno S, Pastrana CL, Fisher GLM, Dillingham MS, Moreno-Herrero F. Nanoscale 2018 Mar; 10: 4579. Combining single-molecule techniques with fluorescence microscopy has...
Structural basis and energy landscape for the Ca(2+) gating and calmodulation of the Kv7.2 K(+) channel
Bernardo-Seisdedos G, Nunez E, Gomis-Perez C, Malo C, Villarroel A, Millet O. Proc Natl Acad Sci USA 2018 Mar; 115: 2395. The Kv7.2 (KCNQ2)...
Molecular clutch drives cell response to surface viscosity
Bennett M, Cantini M, Reboud J, Cooper JM, Roca-Cusachs P, Salmeron-Sanchez M. Proc Natl Acad Sci USA 2018 Feb; 115: 1192. Cell response to...
Membranes Beyond
International Workshop on Status and Perspectives in Research on Membrane Structure and Interaction July 2–4, 2018, McMaster University, Hamilton, Ontario (Canada). Deadlines March 31, 2018....
Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator
Casino P, Miguel-Romero L, Huesa J, Garcia P, Garcia-Del Portillo F, Marina A. Nucleic Acids Res 2018 Jan; 46: 456. The RcsCDB phosphorelay system...
Diseño de fármacos y búsqueda de nuevas dianas
Diseño de fármacos y búsqueda de nuevas dianas 1 Comments Federico Gago, Universidad de Alcalá (España) download La industria farmacéutica, las instituciones académicas y...
Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors
Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragon E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Marquez JA, Massague...
Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL
Romano-Moreno M, Rojas AL, Williamson CD, Gershlick DC, Lucas M, Isupov MN, Bonifacino JS, Machner MP, Hierro A. Proc Natl Acad Sci U S...
3DBIONOTES v2.0: a web server for the automatic annotation of macromolecular structures
Segura J, Sanchez-Garcia R, Martinez M, Cuenca-Alba J, Tabas-Madrid D, Sorzano COS, Carazo JM. Bioinformatics 2017 Nov; 33: 3655. Motivation: Complementing structural information with...