Collepardo-Guevara…Orozco {JACS 137: 10205}

Chromatin Unfolding by Epigenetic Modifications Explained by Dramatic Impairment of Internucleosome Interactions: A Multiscale Computational Study. J Am Chem Soc. 2015 Aug 19;137(32):10205-15. doi: 10.1021/jacs.5b04086.
The presence of acetylated lysine, one of the best known epigenetic marks, induces compaction and rigidification of histone tails in nucleosomes, thereby limiting the extend of internucleosomal interactions and triggering chromatin unfolding.