Rivera-de-Torre…Martínez-del-Pozo {JBC 291: 14109}

Synergistic Action of Actinoporin Isoforms from the Same Sea Anemone Species Assembled into Functionally Active Heteropores. J Biol Chem. 2016 Jul 1;291(27):14109-19. doi: 10.1074/jbc.M115.710491.
A and B are tridimensional estructures of StnI and StnII respectively. They share a 91 % of sequence identity. C plot is a representative example of the synergistic effect developed between StnI and StnII, the hemolytic activity curves of StnI at 3.96 nM (white dots), StnII at 0.04 nM (black dots) and the corresponding StnI:StnII (99:1) 4 nM mixture (black squares) are also shown.