García-Santisteban…Rodríguez {Cell Mol Life Sci 73: 4685}

A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K. Cell Mol Life Sci. 2016 Dec;73(24):4685-4699.
The CRM1 exportin mutant E571K associated with CLL leukemia exhibits a shifted relative affinity for differently charged nuclear export signals (NESs), suggesting an altered nucleocytoplasmic protein transport in this disease.