Brewer…Rizo {Nat Struct Mol Biol 22: 555}

Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nat Struct Mol Biol. 2015 Jul;22(7):555-64. doi: 10.1038/nsmb.3035.
Pseudocontact shifts, induced on nuclei of the Synaptotagmin-I C2B domain (color-coded spheres) by a lanthanide ion attached to the SNARE complex, delineate the dynamic orientation of the C2B domain with respect to the four-helix bundle. The anisotropic magnetic susceptibility tensor of the lanthanide ion is represented by the red and blue isosurfaces.