Structural model for differential cap maturation at growing microtubule ends
Estevez-Gallego J, Josa-Prado F, Ku S, Buey RM, Balaguer FA, Prota AE, Lucena-Agell D, Kamma-Lorger C, Yagi T, Iwamoto H, Duchesne L, Barasoain I, Steinmetz...
Category: Highlights2020
Heat Generation in Single Magnetic Nanoparticles under Near-Infrared Irradiation
Rodriguez-Rodriguez H, Salas G, Arias-Gonzalez JR. J Phys Chem Lett 2020 Mar; 11: 2182. Heat generation by pointlike structures is an appealing concept for...
A multi-modal coarse grained model of DNA flexibility mappable to the atomistic level
Walther J, Dans PD, Balaceanu A, Hospital A, Bayarri G, Orozco M. Nucleic Acids Res 2020 Mar; 48: e29. We present a new coarse...
Dynamics of DNA nicking and unwinding by the RepC-PcrA complex
Carrasco C, Pastrana CL, Aicart-Ramos C, Leuba SH, Khan SA, Moreno-Herrero F. Nucleic Acids Res 2020 Feb; 48: 2013. The rolling-circle replication is the...
Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases
Mideros-Mora C, Miguel-Romero L, Felipe-Ruiz A, Casino P, Marina A. Nat Commun 2020 Feb; 11: 769. Histidine is a versatile residue playing key roles...
Mechanism of Molecular Oxygen Diffusion in a Hypoxia-Sensing Prolyl Hydroxylase Using Multiscale Simulation
Domene C, Jorgensen C, Schofield CJ. J Am Chem Soc 2020 Feb; 142: 2253. The chronic response of animals to hypoxia is mediated by...
Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars
Calabrese C, Uriarte I, Insausti A, Vallejo-Lopez M, Basterretxea FJ, Cochrane SA, Davis BG, Corzana F, Cocinero EJ. ACS Cent Sci 2020 Feb; 6:...
Measuring local-directional resolution and local anisotropy in cryo-EM maps
Vilas JL, Tagare HD, Vargas J, Carazo JM, Sorzano COS. Nat Commun 2020 Jan; 11: 55. The introduction of local resolution has enormously helped...
hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation
Batlle C, Yang P, Coughlin M, Messing J, Pesarrodona M, Szulc E, Salvatella X, Kim HJ, Taylor JP, Ventura S. Cell Rep 2020 Jan;...