High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center
Baños-Mateos S, van Roon AM, Lang UF, Maslen SL, Skehel JM, Lamers MH. Nat Commun 2017 Oct; 8: 855. High-fidelity DNA replication depends on...
Category: Highlights2017
Taming active turbulence with patterned soft interfaces
Guillamat P, Ignes-Mullol J, Sagues F. Nat Commun 2017 Sep; 8: 564. Active matter embraces systems that self-organize at different length and time scales,...
Differential Electrochemical Conductance Imaging at the Nanoscale
López-Martínez M, Artes JM, Sarasso V, Carminati M, Diez-Perez I, Sanz F, Gorostiza P. Small 2017 Sep; 13: 1700958. Electron transfer in proteins is...
Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences
Oliva C, Sanchez-Murcia PA, Rico E, Bravo A, Menendez M, Gago F, Jimenez-Ruiz A. Nucleic Acids Res 2017 Sep; 45: 9030. Mitochondrial endonuclease G...
Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion
Liu X, Seven AB, Xu J, Esser V, Su L, Ma C, Rizo J. Nat Protoc 2017 Sep; 12: 2014. This protocol describes reconstitution...
Potyvirus virion structure shows conserved protein fold and RNA binding site in ssRNA viruses
Zamora M, Mendez-Lopez E, Agirrezabala X, Cuesta R, Lavin JL, Sanchez-Pina MA, Aranda MA, Valle M. Sci Adv 2017 Sep; 3: eaao2182. Potyviruses constitute...
Mechanochemical evolution of the giant muscle protein titin as inferred from resurrected proteins
Manteca A, Schonfelder J, Alonso-Caballero A, Fertin MJ, Barruetabena N, Faria BF, Herrero-Galan E, Alegre-Cebollada J, De Sancho D, Perez-Jimenez R. Nat Struct Mol...
A DNA origami platform for quantifying protein copy number in super-resolution
Zanacchi FC, Manzo C, Alvarez AS, Derr ND, Garcia-Parajo MF, Lakadamyali M. Nat Methods 2017 Aug; 14: 789. Single-molecule-based super-resolution microscopy offers researchers a...
Single molecule high-throughput footprinting of small and large DNA ligands
Manosas M, Camunas-Soler J, Croquette V, Ritort F. Nat Commun 2017 Aug; 8: 304. Most DNA processes are governed by molecular interactions that take...
Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast
Millan CR, Acosta-Reyes FJ, Lagartera L, Ebiloma GU, Lemgruber L, Nue Martinez JJ, Saperas N, Dardonville C, de Koning HP, Campos JL. Nucleic Acids...
De novo active sites for resurrected Precambrian enzymes
Risso VA, Martinez-Rodriguez S, Candel AM, Kruger DM, Pantoja-Uceda D, Ortega-Munoz M, Santoyo-Gonzalez F, Gaucher EA, Kamerlin SCL, Bruix M, Sanchez-Ruiz JM. Nat Commun...
Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis
Mierzwa BE, Chiaruttini N, Redondo-Morata L, von Filseck JM, Konig J, Larios J, Poser I, Muller-Reichert T, Scheuring S, Roux A, Gerlich DW. Nat...